Halothane induction unit

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Rapid induction of halothane anaesthesia in man.

The cardiopulmonary and anaesthetic responses of nine healthy volunteers, breathing concentrations of 1-4% halothane in oxygen, were studied. Supine fasting subjects breathing room air exhaled to residual volume and then inhaled a vital capacity breath of 1, 2, 3 or 4% halothane in oxygen. After a breath-hold of 30-90 s they exhaled and then breathed spontaneously the same anaesthetic mixture f...

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Effect of enzyme induction on nephrotoxicity of halothane-related compounds.

Nephrotoxicity following administration of methoxyflurane has been shown to be directly related to anesthetic metabolism to inorganic fluoride. Enzyme induction should increase metabolic rate and the amount of inorganic fluoride that is released. In vivo studies in Fischer 344 rats show that enzyme induction with phenobarbital or phenytoin increases defluorination following methoxyflurane anest...

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Rapid inhalation induction with halothane-nitrous oxide for myasthenic patients.

Rapid inhalation induction (RII) was successfully employed for patients without myopathy. Inhalatory agents can be used for anaesthetic induction of myasthenics, avoiding the use of neuromuscular blocking agents. We studied the use of RII in 15 myasthenics (MG) and in 15 normal subjects (nMG), measuring induction time (TI), cardiorespiratory effects, complications, and evaluated the patient's r...

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Induction and recovery with enflurane and halothane in paediatric anaesthesia.

One hundred and four infants and children were included in a comparative study of anesthesia with either enflurane or halothane. Induction and recovery were significantly shorter with enflurane than with halothane. There was little difference between the drugs in respect of their postoperative sequelae.

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Comparison between halothane and sevoflurane for adult vital capacity induction.

We have examined the differences in ventilatory characteristics between halothane and sevoflurane when used for adult vital capacity induction of anaesthesia. The study was conducted in a randomized, double-blind manner. After 13 patients had been enrolled, the study was curtailed because the blinded observer thought that there was an unacceptably high incidence of adverse events. After the ran...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 1964

ISSN: 0003-2409,1365-2044

DOI: 10.1111/j.1365-2044.1964.tb00394.x